Several practitioners have requested that we create a transdermal DMSA formulation for their patients. This request was due in large part to the often significant G.I. side effects that can occur when using oral DMSA therapy, and the difficulty in getting children to take DMSA by mouth

Transdermal DMSA has not been used in the past because DMSA exhibits a pungent odor, as well as poor stability in a topical formulation. Our expertise in the design of transdermal medications has allowed us to create a transdermal DMSA formulation that does not display these problems.

In addition, other transdermal chelation agents must be administered every other day. This can be very difficult for both the family and the child taking the chelating agent. Lee Silsby DMSA Transdermal Cream has an advantage over other chelating regimens in that it only needs to be dosed six times per month. Lee Silsby DMSA Transdermal Cream is administered three days in a row, followed by eleven days off. This fourteen-day cycle is then repeated.

Read a patient's inspiring story about our Transdermal DMSA.

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Click here for Transdermal DMSA application instructions.