The treatment of pain is an area of medicine that is of great interest and importance to us. The knowledge we have gained through years of working with both patients and their doctors has proven to be invaluable in helping people recover from injuries and illness.


We specialize in the development of unique topical formulations that can be applied to the skin directly over the injury site that causes the sensation of pain. We have refined these formulations over the past 10 years to obtain excellent skin penetration so that medicines are delivered precisely to the site of injury and only to the site of injury. Through the use of our topical formulations, patients reap the benefits of significantly higher concentrations of medicine at the injury site than can be obtained through oral administration. Topical formulations do not have to travel through the gut, but can begin working immediately at the injury site. In addition, because the medication is applied to only a small area of the body, very little drug is absorbed into the bloodstream to exert side effects. Many drugs that are used in the treatment of pain can cause unpleasant or dangerous side effects, and reducing these side effects through topical application is a significant benefit.

Along with the ability to develop effective topical medications, it is of utmost importance to determine the precise location to which the medicine should be applied. At first glance this would seem to be an easy task: simply apply the medication to the area of the body that hurts. This is, in fact, the way that we began 10 years ago, and it is the way that most compounding pharmacies instruct their patients to apply their medication today. However, we have learned that a majority of patients do not achieve relief from their pain by using this technique. Over time, we came to realize why.

The site of injury is often not the same part of the body where the patient experiences the sensation of pain. When applying a topical medication to the skin, the medicine only penetrates to the area directly below the section of skin where it is applied. If the medication is applied to the area of the body where the patient experiences pain, but the site of injury is elsewhere (as it often is), pain relief will not occur. To achieve optimal results, medication must be applied precisely to the site of injury, not necessarily to the site of pain.

Counseling patients on how to apply medication is therefore of utmost importance to the success of the therapy. Because of this, we generally ask that patients come into the pharmacy to have a short consult on how and where to apply the medication. We also like to discuss with patients the dietary changes and nutritional supplements that can best assist in the healing of injury, improvement of sleep, and reduction of pain. This consult is free of charge. Although this type of consultation is usually needed only when a patient begins using a new medication for the first time, free consultations are available whenever our patients have questions or concerns about the medications and supplements we offer.




The following is a list of pain conditions for which we commonly compound medications:

Arthritis
Ankle Pain
Back Pain
Burning Foot Syndrome
Carpal Tunnel Syndrome
CRPS (Chronic Regional Pain Syndrome)
Diabetic Neuropathy
Fibromyalgia
Foot Pain
Gout
Head, Neck, and Facial Pain
Knee Pain
Migraines
Muscle Spasms
Neuropathic Pain
Post Herpetic Neuralgia
RSD (Reflex Sympathetic Dystrophy)
Shingles
Shoulder Pain
Tennis Elbow
TMJ/TMD (Temporomandibular Disorders)




The following is a list of the delivery vehicles into which we incorporate medications for the treatment of pain:

Topicals - gels, creams, and solutions
Capsules
Suppositories
Nasal sprays
Lozenges
Flavored oral suspensions




Any combination of the following types of medications can be incorporated into these delivery vehicles:

Anti-inflammatory agents
Neuropathic agents
Muscle relaxers
Anti-nausea agents
Magnesium Glycinate Capsules



We recommend that Magnesium Glycinate Capsules be used in combination with prescription medications for patients who experience muscle spasms, neuropathic pain, or difficulty with sleeping.

The mineral magnesium is a critical co-factor in more than 300 enzymatic reactions in the human body, and magnesium deficiency can affect virtually every organ system. Studies have suggested that the typical American diet does not provide people with an adequate amount of magnesium for proper functioning of the body. Supplementation with magnesium can therefore provide nearly universal health benefits.

Most magnesium supplements come in the form of Magnesium Oxide. This form of magnesium is often poorly absorbed by the body and can cause diarrhea in some patients. At our pharmacy, we compound Magnesium Glycinate Capsules as an over the counter supplement. This form of magnesium is very well absorbed by the body.

Positive feedback from our patients who have tried our Magnesium Glycinate Capsules has been overwhelming.

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About Lee Silsby

Lee Silsby Compounding Pharmacy was founded in 1982 by Alan Israel, R.Ph. Our pharmacy is located in Cleveland Heights, Ohio, in a historic fire station. Extensive renovation was done to the inside of the fire station to create a state-of-the-art pharmaceutical facility, while still maintaining the exterior of the building consistent with the standards required for a historical structure.