Benefits of Enhansa for Arthritis
Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae).[1]
Curcumin is an antioxidant compound, effective for removing free radicals from the body. These metabolic by-products may damage cells and harm the body's tissues and organs. Curcumin also has substantial anti-inflammatory activity. It inhibits several enzymes involved in the onset of inflammation, including cyclooxygenase-2, or COX-2. By suppressing this enzyme, curcumin reduces production of prostaglandins, compounds that trigger inflammation and cause swelling and pain.[2]
A preliminary intervention trial that compared curcumin with a nonsteroidal anti-inflammatory drug (NSAID) in 18 rheumatoid arthritis patients found that improvements in morning stiffness, walking time, and joint swelling after two weeks of curcumin supplementation (1,200 mg/day) were comparable to those experienced after two weeks of phenylbutazone (NSAID) therapy (300 mg/day)[3] [4]
Additionally, in a laboratory study published in November 2006 in the journal "Arthritis and Rheumatology," turmeric extract prevented production of COX-2 and other natural chemicals that trigger the onset of inflammation. In another study published in the August 2009 issue of "Journal of Alternative and Complementary Medicine," curcumin extract was effective for treating knee arthritis in patients diagnosed with the condition. Subjects who took curcumin extract had substantially less pain, equivalent to that seen in other subjects who took Ibuprofen.[5]
Despite such significant benefits, numerous studies reveal that regular curcumin supplements are poorly absorbed by the body. [6],[7],[8],[9],[10],[11],[12]
Enhansa is a curcumin supplement with a proprietary extraction process that has shown to be 7 - 8 times more absorbed than standard curcumin extracts.
To learn more or to purchase Enhansa, click here.
[1] http://en.wikipedia.org/wiki/Curcumin
[2] http://www.livestrong.com/article/370160-curcumin-arthritis/#ixzz1Etkm2JOY
[3] http://lpi.oregonstate.edu/infocenter/phytochemicals/curcumin/
[4] 64. Deodhar SD, Sethi R, Srimal RC. Preliminary study on antirheumatic activity of curcumin (diferuloyl methane). Indian J Med Res. 1980;71:632-634.
[5] http://www.livestrong.com/article/370160-curcumin-arthritis/#ixzz1Etkm2JOY
[6] Garcea G, Jones DJ, Singh R, Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration. Br J Cancer. 2004 Mar 8;90(5):1011-5.
[7] Dhillon N, Aggarwal BB. Phase II trial of curcumin in patients with advanced pancreatic cancer. Clin Cancer Res. 2008 Jul 15;14(14):4491-9.
[8] Anand P, Kunnumakkara AB. Bioavailability of curcumin: problems and promises. Mol Pharm. 2007 Nov-Dec;4(6):807-18. Epub 2007 Nov 14.
[9] Sharma RA, Steward WP. Pharmacokinetics and pharmacodynamics of curcumin. Adv Exp Med Biol. 2007;595:453-70
[10] Hsu CH, Cheng AL. Clinical studies with curcumin. Adv Exp Med Biol. 2007;595:471-80
[11] Yang CS, Sang S. Bioavailability issues in studying the health effects of plant polyphenolic compounds. Mol Nutr Food Res. 2008 Jun;52 Suppl 1:S139-51.
[12] Lao CD, Ruffin MT 4th. Dose escalation of a curcuminoid formulation. BMC Complementary and Alternative Medicine 2006, 6:10